Package: fusedTree
Title: Fused Partitioned Regression for Clinical and Omics Data
Version: 1.1.0
Authors@R: 
    c(person(c("Jeroen", "M."), "Goedhart", , "jeroengoed@gmail.com", role = c("aut", "cre", "cph"),
     comment = c(ORCID = "0000-0003-0134-1897")),
     person(c("Wessel", "N."), "van Wieringen", role = "aut", comment = "Author of 'porridge' 'R' package, from which many functionalities have been adopted"),
     person("Thomas", "Klausch", role = "ths"),
     person(c("Mark","A."), "van de Wiel", role = "ths"),
     person("Hanarth Fonds", role = "fnd"))
Description: Fit (generalized) linear regression models in each leaf
        node of a tree. The tree is constructed using clinical
        variables only. The linear regression models are constructed
        using (high-dimensional) omics variables only. The
        leaf-node-specific regression models are estimated using the
        penalized likelihood including a standard ridge (L2) penalty
        and a fusion penalty that links the leaf-node-specific
        regression models to one another. The intercepts of the leaf
        nodes reflect the effects of the clinical variables and are
        left unpenalized. The tree, fitted with the clinical variables
        only, should be constructed outside of the package with the
        'rpart' 'R' package. See Goedhart and others (2024)
        <doi:10.48550/arXiv.2411.02396> for details on the method.
License: GPL (>= 3)
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
Imports: Matrix, splitTools, survival, treeClust, partykit
Suggests: rpart
Repository: https://jeroengoedhart.r-universe.dev
Date/Publication: 2025-08-20 07:57:23 UTC
RemoteUrl: https://github.com/jeroengoedhart/fusedtree
RemoteRef: HEAD
RemoteSha: 6490422905c2e33639a5cc6b6f10b3db96a1d7df
NeedsCompilation: no
Packaged: 2026-10-14 07:49:30 UTC; root
Author: Jeroen M. Goedhart [aut, cre, cph] (ORCID:
    <https://orcid.org/0000-0003-0134-1897>),
  Wessel N. van Wieringen [aut] (Author of 'porridge' 'R' package, from
    which many functionalities have been adopted),
  Thomas Klausch [ths],
  Mark A. van de Wiel [ths],
  Hanarth Fonds [fnd]
Maintainer: Jeroen M. Goedhart <jeroengoed@gmail.com>